ABSTRACT This work proposes an ontological, cosmological, and mathematical reformulation of the Universe, shifting the focus of traditional scientific investigation from the edges of material expansion to the nature of absolute nothingness (zero). It argues that the standard cosmological model (Big Bang) and the chronological count of 13.8 billion years are based on a geometric and linear illusion that confuses the local dynamics of matter with the timeless ontology of reality. Through a method of cognitive emptying, it proposes the hypothesis of the simultaneous coexistence between Absolute Zero (Nothing, ∅), Absolute Infinity (Everything/Universe, U), and Primordial/Informational Intelligence (I). The mathematical formalism of the Universal Equation of Absolute Zero is presented, demonstrating its application in resolving anomalies in quantum mechanics, thermodynamics, electromagnetism, and in the cosmological exclusion of the Multiverse. Finally, the essay maps the pragmatic impact of this paradigm on space exploration through informational warp drives, on the development of Z-bit-based matrix computers, on the instant cure of pathologies, and on the entropic reversal of biological death as a matrix leap.